منابع مشابه
ANP bioactivity in obese hypertensives.
ANP Bioactivity in Obese Hypertensives To the Editor: I write to comment on and to question features of the recent publication from Dessi-Fulgheri and colleagues that appeared in the February issue of Hypertension (Hypertension. 1999:33;658–662). The authors report that a bolus injection of ANP produces greater falls in blood pressure, greater increases in plasma cyclic GMP, and a greater suppr...
متن کاملLeft ventricular hypertrophy in obese hypertensives: is it really eccentric? (An echocardiographic study).
In order to study left ventricular hypertrophy patterns in obese hypertensives, we examined 132 patients with essential hypertension by 2D, M-mode and Doppler echocardiography. The patients were classified in four comparable groups, corresponding to the values of Quetelet's body mass index (BMI) and grades of obesity. More obese hypertensives had on average larger left ventricles with thicker w...
متن کاملInsulin and diastolic dysfunction in lean and obese hypertensives: genetic influence.
We investigated the influence of genetic predisposition to hypertension by studying the relation between insulin sensitivity and left ventricular (LV) mass and function in untreated lean and obese hypertensives. We selected 50 lean hypertensives with normotensive parents (negative family history of hypertension [F-]), 64 lean hypertensives with 1 or both parents hypertensive (positive family hi...
متن کاملAdipose tissue metabolism and CD11b expression on monocytes in obese hypertensives.
At a given degree of adiposity, metabolic and cardiovascular risk varies markedly between individuals. Animal studies suggest that differentially expressed systemic activation of monocytes contributes to the obesity-associated risk variability. We tested the hypothesis that systemic monocyte activation is associated with changes in adipose tissue and skeletal muscle metabolism. In 17 obese hype...
متن کاملLow calorie diet enhances renal, hemodynamic, and humoral effects of exogenous atrial natriuretic peptide in obese hypertensives.
The expression of the natriuretic peptide clearance receptor is abundant in human and rat adipose tissue, where it is specifically inhibited by fasting. In obese hypertensives, plasma atrial natriuretic peptide (ANP) levels were found to be lower than in obese normotensives. Therefore, the increased adipose mass might influence ANP levels and/or its biological activity. The aim of the present s...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1999
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.34.6.e16